Effective Monday, September 29, 2014, American Bio-Clinical Laboratory will only perform the molecular DNA Amplification method for Clostridium difficile testing which will replace our current toxin assay. This assay utilizes molecular DNA Amplification to detect toxin gene sequences associated with toxin producing C. difficile. The assay provides a sensitivity of 98.2% and a specificity of 92.8% when compared to the gold standard of toxigenic culture. This new test methodology provides superior diagnostic accuracy, which eliminates the need for additional or repeat testing of patient samples. This change was made to be in alignment with the latest ASM guidelines for C. difficile testing and to deliver the highest quality patient results. Please note the following specimen and testing requirements.

  • Limit testing to patients with ≥3 non-formed stool specimens per 24 period. Only liquid or soft stools (takes shape of container) are acceptable unless ileus (obstruction) is present. Formed stool will be rejected. Patients may be colonized with toxin-producing C. difficile strains that are not causing illness. Therefore, formed stools are not recommended for testing.
  • Rejection of samples for test of cure. Repeat testing following a positive test (test of cure) is not recommended since patients may carry toxigenic C. difficile for months after clinical cure. Repeat testing following a positive test is appropriate if the patient improves with therapy and relapses after the completion of a treatment regimen (clinical relapse).
  • Testing will be restricted to 1 specimen per 7 days. Molecular tests for C. difficile are highly sensitive and a negative result does not need to be confirmed by a second specimen.

Test ordering information:

Test Name Test Number CPT Sample
CDIFD 653 87493 Liquid or Soft, Unformed Stool

Interpretive Information: Results will be reported as positive or negative for toxigenic C. difficile. Positive test:

  • In adults, metronidazole is the treatment of choice except in cases of severe infection or therapeutic failure.
Negative test:
  • C. difficile molecular tests are highly sensitive. Empiric therapy for patients with diarrhea and negative C. difficile test should be avoided.
For additional C. difficile resources, or if you have any additional questions or concerns, please contact the Microbiology lab directly at 323-222-6688.

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LATEST NEWS AND EVENTS

Effective Monday, September 29, 2014, American Bio-Clinical Laboratory will only perform the molecular DNA Amplification method for Clostridium difficile testing which will replace our current toxin assay. This assay utilizes molecular DNA Amplification to detect toxin gene sequences associated with toxin producing C. difficile. The assay provides a sensitivity of 98.2% and a specificity of [...]

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July 2014 New CBC instrument ABC Labs is now utilizing two Sysmex Hematology Analyzers simultaneously. More information on the analyzer can be found on Sysmex’s website: www.sysmex.com

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June 5, 2014 Welcome Mr. Paul Hoyt, CLS as ABC’s new Clinical Laboratory Manager. It is with great pleasure that we welcome Mr. Paul Hoyt, CLS as our new Clinical Laboratory Manager effective June 9, 2014. Paul received his Major in Medical Technology from California State University and previously worked as CLS and move his [...]

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June 2014 ABC is proud to announce the release of our new Apple App! Reporting System is now available on iPhone and iPad!!! The ABC eLabs application is a Smartphone Application designed specifically for Medical Laboratory Test Services as an extended facility to customers of ABC Laboratories. It provides secure and confidential access to real-time [...]

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May 2014 New Blood Lead instrument by Magellan Diagnostics ABC Labs is now utilizing Magellan Diagnostics’ LeadCare Ultra to run our blood lead tests. More information can be found at LeadCare Ultra’s website.  http://www.lcultra.com/

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WELCOME TO ABC LABORATORIES

American Bio-Clinical Laboratories is a full service medical laboratory in Los Angeles. With many years of experience in diagnostic medicine, we are committed to providing physicians with the highest level of quality, service, and dependability.

American Bio-Clinical Laboratories offers a complete range of clinical determinations. Whether your needs are as simple as routine electrolyte analysis or as advanced as the most obscure of hormone or serological quantitation. With the latest DNA and PCR technology, we can provide a wide breadth of laboratory testing that may be required for the care of your patients.

Our ultimate goal is your complete confidence and satisfaction. Let us prove to you that ABC Labs deserves to be your comprehensive laboratory service.

 

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We at American Bio-Clinical Laboratories take pride in the quality and professionalism of our people. From specimen pick-ups, performances, to the reporting of results, our courteous and efficient staff of pathologists, technologists, technicians and support personnel deliver the highest level of laboratory service possible.